《国际循环》:您认为目前卒中研究方面的热点是什么?另外您可否就未来卒中的治疗做一下设想?Bo Norrving教授:关于卒中,目前有诸多热点议题。我认为最重要的是4.5小时后的再灌注策略(基于显像的决策,血管内技术),更佳的抗凝药物(目前正在试验中),更多针对卒中病理生理学和遗传因素等目标的复健方法。未来的卒中治疗应包括具有最佳费效比的策略,适于医疗资源配置较低的国家和地区,即可在全世界范围内应用。
International Circulation: What do you think are the hot topics on the study of stroke? Also, could you predict the future treatments of stroke?
《国际循环》:您认为目前卒中研究方面的热点是什么?另外您可否就未来卒中的治疗做一下设想?
Prof. Bo Norrving: There are several hot topics for the moment. Highest on my list would be reperfusion strategies beyong 4.5 hours (imaging based decisions, endovascular approaches), better antithrombotic drugs (currently under testing), more targeted rehabilitation techniques based on underlying pathophysiology, and genetic factors causing stroke. Future treatments should also include which strategies are the most cost-efective in low-resource settings world-wide.
Bo Norrving教授:关于卒中,目前有诸多热点议题。我认为最重要的是4.5小时后的再灌注策略(基于显像的决策,血管内技术),更佳的抗凝药物(目前正在试验中),更多针对卒中病理生理学和遗传因素等目标的复健方法。未来的卒中治疗应包括具有最佳费效比的策略,适于医疗资源配置较低的国家和地区,即可在全世界范围内应用。
International Circulation: Is there a difference in the rate of stroke between men and women and if so what is the main reason for this difference? How can we prevent it?
《国际循环》:卒中在男女中发病率有无差异?请问您认为主要的原因是什么?我们应该采取怎样的措施来加以预防?
Prof. Bo Norrving: Women suffer more severe strokes and at a higher age than men. The main reason is probably that women have more atrial fibrillation. The earlier occurence of stroke in men warrants further efforts to change life style factors in men.
Bo Norrving教授:女性更易患严重的卒中,患病年龄高于男性。主要原因可能是女性患心房颤动的更多。卒中发病年龄的提前,提示人们应更为积极地改善生活方式。
International Circulation: What’s your idea about stroke in the younger population?
《国际循环》:关于青年卒中您有怎样的看法?
Prof. Bo Norrving: We need to know more about causes of stroke in the very young (up to 45 years). Currently the cause cannot be found in about a quarter of all cases. I think we find several types of unusual strokes among the young, e.g. those with genetic causes. Several large studies are ongoing on this topic.
Bo Norrving教授:我们需要了解较年轻患者(45岁以下)发生卒中的原因。目前1/4的病例找不到发病原因。我想我们未来将发现年轻患者非常规卒中的一些类型,例如,基因原因所致的。对此,目前正在进行一些大型研究。