高血压患者晚期经常出现心脑肾等靶器官损害,微量蛋白尿(MAU)是靶器官损害危险因素,可用有效措施预防和逆转高血压患者MAU的出现。MAU被认为与高血压、糖尿病患者的肾损害有关,可以预测这些患者的心血管事件。大量的临床研究数据显示降低MAU可以减少心血管事件,未来的研究应更多地关注如何发现更加有效的手段来预防高血压患者MAU及心血管事件的发生。
《国际循环》:看食品配料表的时候,我们会发现几乎所有加工食品都含有果糖。可能西方国家在加工食品中添加的果糖更多。这是否会影响MAU的发病率?工业化程度较低的国家是不是较少应用果糖?我知道,有很多因素会影响MAU的发生,所以可能不好判断。
<International Circulation>: Almost any processed food you look at the ingredient list so because of this large content maybe more westernized countries probably have higher content. Does this affect the incidence of MAU and have you really seen the evidence that maybe less industrialized nations use less of this fructose? I know there are many factors so it may be difficult to judge.
Ritz教授:我可能没法直接回答你的问题。不过,我们可以看看在MacGregor教授开展的一项研究中,果糖对英国伦敦的人群会产生何种影响?该研究观察了饮用可口可乐(注:含有果糖)的情况和盐摄入量的关系。结果显示,盐摄入量较高者体重更高,因为这些人摄入的热量更高,而很大一部分热量是来自可口可乐。因此,这项研究启示我们,仅仅解决一个问题是不够的,同时针对西方饮食配料方面目前存在的多个问题可能更加有效。
Prof. Ritz: Maybe not a direct answer to your question but just to show how this impacts the London group by MacGregor looked at the relation between Coca Cola consumption and salt consumption and they found that those who had high salt had higher weight because they consumed more calories and a large proportion of it was through Coca Cola. So it shows that going at one single item is probably not optimal to reduce some of the current components of western diets would be more helpful and effective.
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