SSSS Study: Reduction of cardiovascular events by simvastatin in nondiabetic coronary heart disease patients with and without the metabolic syndrome: subgroup analyses of the Scandinavian Simvastatin Survival Study -国际循环网

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SSSS Study: Reduction of cardiovascular events by simvastatin in nondiabetic coronary heart disease patients with and without the metabolic syndrome: subgroup analyses of the Scandinavian Simvastatin Survival Study

作者:国际循环网日期:2004/10/12 0:00:00

OBJECTIVE: To assess the effect of simvastatin treatment on the risk of cardiovascular events in nondiabetic patients with coronary heart disease (CHD) with and without the metabolic syndrome， as defined by the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP-III).

Diabetes Care. 2004 Jul;27(7):1735-40. Pyorala K， Ballantyne CM， Gumbiner B， Lee MW， Shah A， Davies MJ， Mitchel YB， Pedersen TR， Kjekshus J; Scandinavian Simvastatin Survival Study (4S). Department of Medicine， Kuopio University Hospital， Kuopio， Finland. kalevi.pyorala@uku.fi

OBJECTIVE: To assess the effect of simvastatin treatment on the risk of cardiovascular events in nondiabetic patients with coronary heart disease (CHD) with and without the metabolic syndrome， as defined by the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP-III).

RESEARCH DESIGN AND METHODS: Subgroup analyses were performed on data from 3933 nondiabetic patients with clinically established CHD， serum total cholesterol level 5.5-8.0 mmol/l， and serum triglyceride level

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